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Fourth, the analyses with dementia subtypes should be considered exploratory and interpreted with caution, because the diagnoses were not necessarily biomarker-confirmed, and the referent standard in the validation studies [38, 39] was not biomarker-confirmed diagnoses
Considering the absence of a consensus on diagnostic methods, screening criteria, and treatment for vitamin B12 deficiency in patients with T2D receiving metformin, this narrative review had the following aims: (1) Discuss the diagnostic criteria for vitamin B12 deficiency and the utility of vitamin B12 biomarkers
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