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This practice aims to promote slower weight loss compared to standard doses, which may help mitigate rapid facial volume loss that causes the Ozempic face

Based on direct head-to-head evidence from the SUSTAIN 7 trial, semaglutide produces statistically greater reductions in HbA1c and approximately twice the weight loss compared with dulaglutide at matched dose levels

Preclinical data from the CagriSema program demonstrate pronounced additive metabolic endpoint changes when both pathways are activated simultaneously, exceeding either agent alone in study models

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