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NICE guidance including Technology Appraisal TA875 (semaglutide 2.4 mg for managing overweight and obesity), Clinical Guideline CG189 (Obesity: identification, assessment and management), and Public Health Guidance PH53 (Weight management: lifestyle services for overweight or obese adults) recommends a structured, tiered approach to weight management
Reports suggest a surge in off-label use among non-diabetic individuals driven by online hype
Approximately 70% of American people are obese or overweight, which is a serious health condition linked to a number of the top causes of mortality, such as cardiovascular diseases
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