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doi: 10.3390/ijms22095010, 5 AoyamaK.MatsubaraK.FujikawaY.NagahiroY.ShimizuK.UmegaeN.et al
Both peptides coordinate with copper through the histidine at position two, which is the structural feature that makes copper delivery possible in both cases
Early research suggests that applying a cream containing 5% alpha-lipoic acid to the face may reduce fine lines and roughness due to sun damage
This means side effects may linger for a bit after stopping, but most people see them improve within a week
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