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With existing clinical data on Polmacoxib limited to only two previous studies, this prospective, multicenter, open-label observational study contributes meaningful real-world insights by examining its effectiveness, onset of action, and safety and tolerability over an eight-week period in everyday Indian clinical practice

Cardiovascular manifestations evolve from hypertension and tachycardia to myocardial depression, profound bradyarrhythmias, widened QRS complexes, and refractory ventricular fibrillation if plasma levels exceed roughly 10 g/mL

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