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One review concluded that vitamin B12 plays a key role in fat metabolism, noting that a deficiency could be linked to increased fat accumulation and obesity ( Another animal study found that severe vitamin B12 deficiency led to a significant increase in body fat percentage and cholesterol levels in pregnant mice ( Whats more, one animal study showed that administering B vitamins to rats fed a high fat diet reduced weight gain and increased levels of several enzymes that influence metabolism, compared with a control group ( However, current evidence is lacking, and additional high quality studies are needed to determine how vitamin B12 may affect metabolism and body fat in humans

The skin and the muscles under the skin cover nerves, blood vessels and bones

Typically, effects like increased energy, better mood, or improved metabolism can last from a few days up to two weeks, depending on the nutrient, dosage, and your bodys metabolism

Diagnosis of Vitamin B12 Deficiency The diagnosis of vitamin B 12 deficiency has traditionally been based on low serum vitamin B 12 levels, usually less than 200 pg per mL (150 pmol per L), along with clinical evidence of disease

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