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Summary of completed and ongoing clinical trials of GLP-1RAs for neurodegeneration In summary, clinical trials investigating GLP-1RAs in neurodegenerative diseases have yielded contrasting outcomes

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When tirzepatide earned FDA approval for obesity under the brand name Zepbound, it marked the first dual-action GLP-1/GIP therapy officially recognized for chronic weight management

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doi: 10.1016/j.chest.2021.07.009 276 BeitlerJRThompsonBTBaronRMBastaracheJADenlingerLCEssermanLet al

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