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doi: 10.3389/fimmu.2021.652252 155 LabarrereC

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Bar-Or A, Grove RA, Austin DJ, et al

RSL3 suppresses spheroid formation and viability, and halts migration of PTC cells in vitro We postulated that the RSL3-mediated suppression of thyroid tumor cell viability is a ferroptosis pathway-dependent process, therefore, we treated K1 cells with a lethal dose of RSL3 alone and in the presence of either a ferroptosis inhibitor Fer1, or a pan caspase inhibitor, Z-VAD-FMK (ZVAD) and measured cell viability

The relative-mass argument This connects to the second insight from the Langer work