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Caution is advised in patients with Leber optic atrophy, a genetic disorder caused by chronic cyanide intoxication (such as from smoking, alcohol or some plants), against the use of cyano-B12 due to its cyanide moiety, whilst hydroxo-B12 is a cyanide antagonist and can therefore be used in these patients
MOTS-c is typically administered in the morning to align with metabolic activity cycles
The role of MAO in MPTP toxicitya review
Based on this analysis, specific recommendations and suggestions were developed for each disorder
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