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The work in the recently published study was done before the coronavirus outbreak, with the researchers testing HCQ/CQ and metformin for pancreatic cancer and coming up with this perhaps, serendipitous finding
2 Volek JS, Kraemer WJ, Rubin MR, et al
The half-life difference between the two forms is roughly 8 days versus minutes, so the dosing frequency mismatch is dramatic
You can check out their YouTube channel for deeper dives into related subjects
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