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Thiamine deficiency adversely affects the activity levels of these enzymes, with TK, through thiamine-dependent erythrocyte transketolase (ETK) activity, common biomarkers of thiamine status, since it is particularly sensitive to thiamine levels and AKD often exhibiting the earliest detectable changes (41)
The characteristics of non-healing wounds include long-term or excessive inflammation, persistent infection, microbial biofilm formation, and the incapacity of dermal or epidermal cells to react to repairing stimuli ( Hydrogels have been found to effectively improve wound healing and functional recovery (Zhang et al., 2020)
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Hamilton, Matthew J
