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This study was conducted after approval by the Research Ethical Committee of Faculty of Medicine, Ain Shams University with approval number (FMASU M S 630/2022) in 22/6/2022

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Triglyceride (TG) level The data demonstrating a disturbance in the metabolism of long-chain acylcarnitines in the congenital hypothyroid patients with fatigue might be due to an insufficient CPT-I activity prompting us to ask whether the long-chain fatty acids are diverted for use in the biosynthesis of TG (Fig 1b)