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Novel GLP-1 mimetics in diabetes: lixisenatide and albiglutide

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Common Off-Label Uses Polycystic Ovary Syndrome (PCOS) Some providers prescribe GLP-1s to improve insulin resistance, weight-related symptoms, and menstrual regularity Small studies show potential benefits Infertility / Preconception Support Off-label use in people trying to conceive (especially those with an elevated BMI and/or insulin resistance)

doi:10.3389/fphys.2024.1330171 Hygum K, Starup-Linde J, Harslf T, Vestergaard P, Langdahl BL