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This side effect is relatively unique to retatrutide and may relate to the glucagon receptor component
The incretin concept was later developed further by identifying the gut hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) as main incretin hormones (6, 7) and the development of GLP-1 as a potential treatment of type 2 diabetes (8)
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