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Methylcobalamin, a form of B12, is particularly essential for synthesizing neuronal lipids, regenerating axonal nerves, and exerting neuroprotective effects, potentially improving conditions such as Alzheimer's disease, Parkinsonism, and dementia, while also serving as an approved treatment for peripheral neuropathy

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Als2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth