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Meta-analyses of the effects of DPP-4 inhibitors, SGLT2 inhibitors and GLP1 receptor analogues on cardiovascular death, myocardial infarction, stroke and hospitalization for heart failure
Both options are especially helpful for people who struggle with appetite regulation or emotional/behavioral eating patterns
Every single case resolved with hydration and temporary treatment pause
However, there is lack of RCTs in T1D using the newest generation of GLP-1RA or dual GLP-1/GIP agonists, which are associated with significantly more weight loss
Any ranking of the two is cross-trial inference, not direct evidence
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