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[10] In clinical research settings and certain intensive protocols (such as addiction detoxification), much higher NAD+ dosages have been utilized
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Who May Need Extra Caution Extra caution may be needed for patients who are pregnant or trying to become pregnant, have active cancer or a cancer history requiring specialist input, have autoimmune disease, have clotting concerns, use immune-modifying medication, have uncontrolled diabetes, have significant kidney or liver disease, or are scheduled for surgery