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Lastly, Ex-4 also protects the AGE-induced activation of receptor AGE signaling pathway, which is responsible for the inflammation and oxidative stress induced by AGEs [66]
A novel interaction of diethyldithiocarbamate with the glutathione/glutathione peroxidase system
Schaab, C., Geiger, T., Stoehr, G., Cox, J
10.1073/pnas.78.11.6858 Proc
The results were not straightforward, since glucose intolerance in GIP or GLP-1 receptor KO mice were reported only in eight of the arms, whereas normal glucose tolerance was reported in five arms
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