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People with type 1 diabetes shouldnt have to work so hard to keep their weight down. Heart and kidney protection: Organ-protecting agents While GLP-1s and SGLT-2s began as glucose-lowering medications, the research shows that these drugs also protect the heart and kidneys in people with and without type 2 diabetes

Cells were imaged 24 hours after seeding in RPMI-1640 buffer without phenol red +/ 100 nM exendin-4 by time-lapse microscopy every 12 seconds for 11 minutes in a 37C heated chamber using a Leica Stellaris 8 inverted confocal microscope with a 40x/1.2 oil immersion objective with excitation wavelengths of 440 and 580 nm and emission wavelength of 620 nm

BMC Endocr Disord

The brain is particularly vulnerable to oxidative stress due to its high oxygen consumption, abundant polyunsaturated fatty acids, and relatively modest antioxidant defenses compared to other organs [1][2][48]

Prefilled multi-dose pens and autoinjector devices have further elevated the ease of self-administration via the subcutaneous route