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Iloprost and vitamin C attenuates acute myocardial injury induced by suprarenal aortic ischemia-reperfusion in rabbits
DOI:10.1007/s00277-014-2050-z [ Links ] 45
Based on this, an investigator-initiated, phase III, double-blind, randomized controlled trial was performed to evaluate the efficacy and safety of high-dose selenium (2000 g/day) intravenously in a 1:1 ratio for the prevention of CIPN in 68 platinum-sensitive cancer patients treated with paclitaxel, carboplatin, and bevacizumab [110]
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Transforming growth factor-1 (TGF-1) can induce the EMT phenotype in melanoma cells and upregulate the levels of GPX4 and SLC7A11, while gambogenic acid, a xanthone derived from traditional Chinese medicine Gamboge, can promote ferroptosis by inhibiting the SLC7A11/GPX4 pathway in melanoma cells stimulated by TGF-1
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