Switching from Semaglutide, a GLP-1 receptor agonist, to Zepbound (Tirzepatide) is possible, but should be done under the supervision of your healthcare provider
In a later interview with People , published in December 2025, Winfrey revealed that just six months after starting GLP-1s, shed decided to see if she could beat the medication by stopping taking them
Physician-guided treatments designed to help you look and feel your best
Graaf Cd, Donnelly D, Wootten D, Lau J, Sexton PM, Miller LJ, et al

Key areas of focus include: Regulatory and Scientific Foundations: Current FDA scientific thinking on generic GLP-1 product development, Product-Specific Guidance (PSG) development, and in vivo BE studies for GLP-1 oral products Active Pharmaceutical Ingredient (API) Characterization and Manufacturing: Comprehensive approaches to demonstrating API sameness, analytical characterization strategies, impurity profiling, and sameness assessment for peptide products Recombinant Peptide Production: Best practices for controlling host cell impurities, regulatory expectations, and risk assessment strategies Oral GLP-1 Formulation Development: Formulation and delivery innovations, bioequivalence study design for highly variable products, absorption enhancement technologies, and drug product quality expectations Device User Interface and Human Factors: Comparative analyses (CA) of device user interfaces, Comparative Use Human Factors (CUHF) study design and case examples, alternative approaches, and device platform strategies Device Quality and Integration: Quality considerations for generic injectors, drug-device interface and compatibility, manufacturing quality control, and submission coordination strategies Join us for an immersive two-day experience featuring presentations from leading experts in regulatory agencies, pharmaceutical industry, and academia
