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The conversation around GLP-1 medications has to expand beyond the scale, because what we are seeing clinically is that some patients experience a flattening of hedonic response that goes well beyond food, touching motivation, social engagement, and overall sense of pleasure in daily life

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[13-18] These trials had similar designs: adults who had a history of heart disease or stroke, or who were at high risk of heart disease, were given a pill containing high doses of vitamins B6, B12, and folic acid or a placebo

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The theoretical framework for synergy rests on well-established principles of systems biology

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If your vial sat out overnight after reconstitution, it's compromised beyond recovery

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