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doi: 10.1111/dom.12932, 9 BoothM
By activating GLP-1 receptors in the pancreas, brain, and digestive system, semaglutide triggers several beneficial effects: Increased Insulin Secretion : Stimulates the pancreas to release more insulin when blood sugar levels are high
Because the preservative protects the solution between uses, it reduces the risk of bacterial contamination from repeated needle insertions
A nationwide cohort study from Sweden and Denmark found no significant increase in suicide deaths among GLP-1 RA users compared to Sodium-glucose cotransporter-2 (SGLT2) inhibitors, and even reported a lower incidence of combined suicide and self-harm outcomes (HR 0.83) [47]
One study evaluated a small group of people with schizophrenia taking both the antipsychotic medication clozapine and semaglutide (the GLP-1 medication in Ozempic and Wegovy)
