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This is like the unexpected plot twist that can catch us off-guard
Compare this to subcutaneous injection at 80-95% bioavailability
No single peptide addresses all of these simultaneously
TermannsenADClemmensenKKBThomsenJMNrgaardODazLJTorekovSSet al
For recycling, cells were incubated with agonists at 37 C for 15 min, followed by endocytosis arrest at 4 C, surface label removal as above, 30 min incubation at 37 C with 10 M exendin(9-39) to prevent further internalization, and a second round of surface label removal at 4 C
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