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The efficacy and safety of beta-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

Common side effects can include temporary redness, swelling, bruising, or tenderness at the injection site

Brain behavior Immun (2018) 73:85114

After initial correction, some individuals may require ongoing maintenance injections (often monthly) if they cannot adequately absorb B12 from diet or oral supplements