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Bryan Mabry MD May 6 4 min read GLP-1 medications have gained attention primarily for their role in managing type 2 diabetes and obesity
Prescription doses can be up to 4g/day.[ref] With the research pointing to CD44 and increased liver damage markers, researchers used mouse models and human genetics to understand which SNP (single nucleotide polymorphism) causes the increased risk.[ref][ref] What is CD44
Frontiers in Cell and Developmental Biology, 13 , 1633166 Shang, Y., Song, N., He, R., & Wu, M
Pioglitazone , a thiazolidinedione, directly enhances insulin sensitivity in adipose tissue and muscle but carries risks of weight gain, fluid retention, and bone fractures
Murdoch C, Muthana M, Coffelt SB, Lewis CE
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