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The most commonly reported side effects for both agents are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
Novo Nordisk ran the REDEFINE Phase 3 program to test CagriSema in adults with obesity
Mood Changes: Increased irritability, depression, or anxiety
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When nutrientsespecially fats, proteins, and soluble fibersinteract with these cells, they stimulate GLP-1 release. Research has found that some dietary modifications are effective at promoting GLP-1 secretion, namely high-fiber foods and those that provide nutrients like fatty acids
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