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Similar content being viewed by others Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a class of medication that mimic the effects of glucagon-like peptide-1 (GLP-1), an endogenous, gut-derived incretin that is released in response to a meal [1]

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Taking your injection significantly early or late (more than 23 days off schedule) can disrupt the steady-state balance and lead to inconsistent results or side effects

Many people find that room-temperature injections are more comfortable

Start low (3 to 5 grams a day) and titrate up slowly to avoid bloating, advises Reisdorf