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Important safety considerations include risks of acute pancreatitis (seek medical attention for severe abdominal pain with or without vomiting), gallbladder disease, dehydration, and potential worsening of diabetic retinopathy with rapid improvement in glucose control
Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGlu as precursor for neuronal glutathione
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Medication orders lacking structured information on total days supplied were excluded, as these were frequently free-text entries unsuitable for reliable longitudinal analysis
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