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Researchers utilize DSIP to examine how endogenous peptides coordinate sleep-wake cycles with neuroendocrine stress responses, particularly focusing on its potential to normalize sleep patterns disrupted by stress or circadian disturbances in experimental models
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Treatment usually begins with a low dose, which can later be adjusted by a doctor to balance effectiveness and tolerability
Despite promising Phase 2 results and an excellent safety profile, the compound could not demonstrate sufficient efficacy in the larger confirmatory trial to justify the investment required for continued pharmaceutical development toward regulatory approval
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