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Even more, some polyphenols can act as plant estrogens or SERMs to alleviate the cartilage degeneration associated with menopausal OA (46)

Long-term hemodialysis has a positive effect on IR ( In addition to being a risk factor for CKD onset and progression, IR is also involved in the increased cardiovascular (CV) risk in this population

A further major limitation in our understanding of the cardiovascular effects of MNPs in humans stems from the fact that many mechanisms identified in experimental models have not yet been validated clinically

Redox Biol (2018) 15:490503

Vitamin C helps maintain glutathione in its active form and supports antioxidant function