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Subsequent Friedlnder reactions generate quinolinepeptide hybrids, some of which contain stable biaryl atropisomeric axes

These findings provide a foundation for understanding the etiology of EC and open possibilities for early prevention and intervention

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No entanto, ainda existem desafios a serem superados, como a necessidade de ensaios clnicos mais robustos para validar os achados preliminares e a identificao dos perfis de pacientes que mais se beneficiariam desses tratamentos