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decreasing glucagon production reduces the amount of endogenous glucose produced by the liver (see Figure)

Advanced research applications include tissue-specific studies where FOXO4-DRI has demonstrated broad regenerative effects across multiple organ systems

16 , e2006649 (2018)

Because of the limitations of this type of study, the research cant prove that hormone therapy directly caused the additional weight loss but it supports the idea that estrogen may influence how some women respond to GLP-1s