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This finding holds particular importance given no medications currently target both alcohol reduction and smoking cessation simultaneously

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The result is that an ADC manufacturer must typically navigate multiple third-party patent estates to bring a product to market, and the FTO analysis for an ADC is substantially more complex than for either a naked antibody or a small-molecule drug

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At the same time, B12 insufficiency in the liver leads to shrinking of the intestinal cells and malabsorption of nutrients (including B12 itself), leading to a cycle of worsening B12 deficiency