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Sections of 5-m thickness were stained with hematoxylin and eosin (H&E) and Sirius Red (performed at Narabyouri Research Co., Nara, Japan)

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1 The findings showed: Those not taking GLP-1 medications showed significantly more MS disease progression Higher risk of brainstem dysfunction (4.36% risk difference) Higher risk of cerebellar dysfunction (4.54% risk difference) Higher risk of bowel and bladder dysfunction (4.98% risk difference) As a retrospective analysis, this study has limitations including potential confounding factors, and definitive randomised controlled trials are needed to confirm any disease-modifying effects of GLP-1 medications in MS

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However, in some patients the tumors may be completely asymptomatic