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Naturally, B12 deficiency can lead to many health-related issues, the most common being weight gain

Why Vitamin B12 is Important Vitamin B12, or cobalamin, is a water-soluble vitamin that plays an important role in overall health and well-being

Interactions with Medications: Vitamin B12 has the potential to interact with certain medications, including diabetic prescriptions, metformin, proton pump inhibitors, antagonists and antibiotics

Vitamin D, which humans absorb through UV rays or get from a few foods, such as fish oils, supports the immune system and fights inflammation

Still, more is not automatically better, and frequency should be guided by a licensed provider who knows your history