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Niazi explains that tirzepatide is a newer dual-agonist that targets both the GLP-1 receptor and the GIP (glucose-dependent insulinotropic polypeptide) receptor, which he says offers superior metabolic regulation and appetite suppression. Mounjaro is currently FDA-approved for type 2 diabetes, and Zepbound is also FDA-approved for weight loss

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The transcript and protein profiling revealed an upregulation in PPAR signalling and factors related to fatty acid biosynthesis and metabolism (Fig

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