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The specificity of peptide-receptor interactions allows for precise modulation of biological pathways

10.1021/acs.molpharmaceut.1c00511 56 LiuD.JinF.ShuG.XuX.QiJ.KangX.et al (2019b)

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The effects are produced mainly by the increase in nitric oxide (NO), cyclic AMP (cAMP), mitogen-activated protein kinases (MAPKs), matrix metalloproteinases (MMPs), angiogenic growth factors like vascular endothelial growth factor (VEGF) and upregulating the expression of endothelial-B receptor (ET-B) [12]

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