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Appetite and Gut Hormones Response to a Putative -Glucosidase Inhibitor, Salacia Chinensis, in Overweight/Obese Adults: A Double Blind Randomized Controlled Trial

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This is due to the fact that obesity enhances the production of ROS in mitochondrial, which can damage the lipid membranes, proteins, and enzymes of the respiratory chain in the mitochondria, as well as DNA (77)

Only one trial in adults has reported a transient increase in serum lipid levels, which is potentially due to the lipolytic effects of elevated GH levels [12]

6 Additional studies are currently under way to investigate if this effect is seen with other GLP-1 RAs