What causes Vitamin B12 Deficiency or Folate Deficiency
Anyone taking methyl-donor-sensitive medications (some psychiatric drugs, methotrexate, methylated B-vitamin protocols at high doses): NNMT shares the methyl donor SAM, so theoretical interactions exist
It also pairs well with a Bcomplex formula that includes other B vitamins like B6 and folate, since these work together on energy production, brain health, and mood. If you are taking highdose supplements or prescription medications, it is always wise to let a healthcare professional review your regimen to avoid unnecessary overlaps or interactions
If your protocol is headed toward these higher doses, switching to the 1ml reconstitution when you move past 5mg simplifies the process
For comparisons between two specific groups, the MannWhitney U test was applied