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Fibre adds volume, stretches the stomach and feeds beneficial gut bacteria that support appetite regulation

Many patients report eating smaller portions without conscious effort or feeling less preoccupied with food planning

The original preclinical study used a GCGR antibody antagonist to isolate the GCGR contribution in DIO mice: GCGR blockade significantly blunted weight loss and blocked the LY3437943-induced increase in energy expenditure without affecting caloric-intake reduction