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SURMOUNT-1 showed average weight loss of 21.4% at 10mg over 72 weeks

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beyond 6 months, the metabolic monitoring requirements and potential need for adjunct interventions narrow the cost gap.

Females exhibited higher total reactive oxygen species (ROS) levels and hyperproliferation of T-cells, while males showed normal overall ROS but suffered from pronounced mitochondrial lipid oxidative damage mediated by a failure in Glutathione Peroxidase 4 pathways

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