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Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)
Liver transplantation can be taken into consideration if necessary
Baserga R et al
The increase in total glutathione abundance, however, is coupled with an unbalanced activation of glutathione metabolic pathways
The cardiometabolic consequences of impaired glutathione homeostasis are profound
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