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For eligible adults with clinically significant obesity, MHRA-approved options include semaglutide (Wegovy, assessed in NICE TA875) and tirzepatide (Mounjaro, assessed in NICE TA1026), both available through NHS pathways with appropriate clinical oversight
How DSIP Works in Your Brain and Body Understanding how DSIP produces its effects requires looking at several interconnected systems in your body
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Side Effects and Tolerability: What To Expect With Each Medication Both semaglutide and tirzepatide carry similar side effect profiles dominated by gastrointestinal symptoms during initial weeks and dose increases
we help you manage potential side effects and monitor your progress
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