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Retatrutide exhibits triple agonist activity against GCGR, GIPR, and GLP-1R, with EC 50 values of 5.79, 0.0643, and 0.775nM, respectively [1]

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The medications are administered via subcutaneous injection, typically weekly (semaglutide, tirzepatide) or daily (liraglutide)

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[PMID: 40649955] PubMed record related to this compound for laboratory literature review

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