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Animal studies have also shown that portal vein GLP-1 weakens intestinal fat absorption and chylomicron production through the vagal enteric-brain-liver axis, and reduces postprandish and fasting blood lipids [79]

But many patients wonder what happens if they decide to pause treatment, run out of medication, change insurance, or switch to another injectable such as Tirzepatide (Mounjaro/Zepbound)

Allow full absorption

This energy-burning mechanism is an additional component of this therapy, which is not present in semaglutide and tirzepatide therapy

49 This trial demonstrated that the gastro-duodenal-jejunal bypass sleeve could be an effective treatment option for the long-term management of morbid obesity