As a 2025 narrative review in PubMed confirming BPC-157 promotes angiogenesis, accelerates tendon and bone healing, and protects gastrointestinal lining across multiple animal models notes, the current evidence base is robust in preclinical settings with no approved human trials completed to date
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Off-label in the US for cosmetic use but with a long safety history
J Biol Chem 276:1668316689 Lee JG, Kang DG, Yu JR, Kim Y, Kim J, Koh G et al (2011) Changes in adenosine deaminase activity in patients with type 2 diabetes mellitus and effect of DPP-4 inhibitor treatment on ADA activity
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