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331-333 ALA may also affect cardiovascular risk factors, with one study showing that ALA treatment improved vascular tone in obese or overweight children and adolescents
Further optimization led to once-weekly administration instead of daily administration, longer-lasting presence in plasma (blood), superior target outcomes (i.e
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For instance, a retrospective observational study on hospitalized elderly patients with type 2 diabetes found that patients treated with GLP-1 receptor agonists combined with basal insulin had an increase in limb skeletal muscle mass, while those treated only with basal insulin showed a slight decrease, suggesting that under specific clinical management conditions, GLP-1 receptor agonists may help maintain muscle mass [61]
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