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That is, the ADA recommends that one of these agents be considered as add-on therapy irrespective of the need for glucose lowering

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A phase 2 clinical trial, published in The New England Journal of Medicine, included 338 adults with a body mass index (BMI) of 30 or greater, or a BMI between 27 and 30, with at least one weight-related comorbidity to assess the efficacy and benefits of retatrutide

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