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Other investigators have attempted to facilitate the availability of central brain-derived neurotrophic factor (BDNF) with injections of human BDNF directly into the patients brain with minimal positive results [17]

Under-dilution creates overly concentrated solutions that may irritate injection sites

Typically a weekly intramuscular injection

Retinol accelerates cell turnover and has some collagen-stimulating effects, but it can cause irritation, dryness, and photosensitivity making it less ideal for patients with sensitive skin or those in sun-intensive environments like Ponte Vedra Beach